鍙ょ喚鏄� 鍓富浠婚啱(y墨)甯�
鎿呴暦(zh菐ng)锛氭硨灏跨郴鑵槫銆佹硨灏跨郴绲�(ji茅)鐭�銆佸墠鍒楄吅鐤剧梾鐨勫井鍓�(chu脿ng)鑵旈彙瑷烘不....[瑭虫儏]
鍐ぉ鍚冧粈涔堝ソ
鍐ぉ鍚冧粈涔堝ソ锛熸皯闁撴祦鍌斥€滃咕椤嗘潖妗冧笁鎶婄伀锛屾棩椋熸ⅷ涓嶇偤澶氣€濈殑璜鸿獮(y菙)锛岃(shu艒)鏄庡椋熸ⅷ鏈夌泭鐒�(w煤)瀹�銆備腑閱�(y墨)瑾�(r猫n)鐐�锛屾ⅷ鏈夌敓娲ユ娓�銆佹鍜冲寲鐥�銆佹竻鐔遍檷鐏�銆侀(y菐ng)琛€鐢熻倢銆佹饯(r霉n)鑲哄幓鐕ョ瓑鍔熻兘锛屾渶閬╁疁浜庡啲瀛ｇ櫦(f膩)鐔卞拰鍏�(n猫i)鐔辩殑鐥呬汉椋熺敤銆傚挨鍏跺皪(du矛)鑲虹啽鍜冲椊銆佸皬鍏掗ⅷ(f膿ng)鐔便€佸捊骞插枆鐤�锛屽ぇ渚跨嚗绲�(ji茅)鐧ヨ純鐐洪仼瀹�銆傞倓鍙公鍔╂秷鍖�銆佷績閫�(j矛n)椋熸锛屽苟鏈夎壇濂界殑瑙ｇ啽鍒╁翱浣滅敤銆傛瘡澶╁悆涓婁竴鍒板叐鍊�(g猫)姊ㄥ彲鏈夋晥绶╄В鍐嚗銆傚搴啱(y墨)鐢熷湪绶氶牷閬撶偤寤ｅぇ缍�(w菐ng)鍙嬫彁渚涘啲澶╁悆浠€涔堝ソ鏈€鏂版渶娆�(qu谩n)濞佺殑鐨勭浉闂�(gu膩n)璩囪▕,濡傛灉鎮ㄦ湁鑸堣叮鎯充簡瑙ｄ竴涓嬪啲澶╁悆浠€涔堝ソ,璜�(q菒ng)闂�(gu膩n)娉ㄥ搴啱(y墨)鐢熷湪绶�銆�
鍐棩宸茶繎锛屼綔鐐鸿嚚搴婁竴绶氳啝楂斿京(f霉)铇囦娇鐢ㄧ殑缇ヤ箼鍩烘穩绮夛紙HES锛変技涔庝篃闈㈣嚚鍤�(y谩n)瀵掋€傛瓙娲查噸鐧ラ啱(y墨)瀛�(xu茅)鏈�(hu矛)鐧�(f膩)甯冨叡璀�(sh铆)锛氫笉鎺ㄨ枽鍦ㄥ毚(y谩n)閲嶈喛姣掔櫏鎮ｈ€呬娇鐢ㄥ垎瀛愰噺200kDa鍜�/鎴栧彇浠ｇ礆(j铆)0.4鐨凥ES鐢�(ch菐n)鍝�銆傘€婃柊鑻辨牸铇啱(y墨)瀛�(xu茅)闆滃織銆嬩笂鐧�(f膩)琛ㄧ殑涓€闋�(xi脿ng)涓归亥鐨勮嚚搴婅│椹�(y脿n)鎸囧嚭锛堣縿浠婃ǎ鏈噺鏈€澶х殑闂�(gu膩n)浜庢柊鍨婬ES鐨勫涓績RCT鐮旂┒鈥斺€�6S鐮旂┒锛夛細6%HES 130/0.42鐢ㄤ簬鍤�(y谩n)閲嶈喛姣掔櫏寰�(f霉)铇�锛�90澶╂浜″拰鐧�(f膩)鐢熻厧琛扮鐨勯ⅷ(f膿ng)闅�(xi菐n)鏄庨’楂樹簬鏅堕珨娑叉灄鏍兼皬娑诧紝閫欎竴鐧�(f膩)鐝�(xi脿n)灏�(du矛)浜嶩ES渚�(l谩i)瑾�(shu艒)鐒�(w煤)鐣伴洩涓婂姞闇�銆� 甯哥敤鐨凥ES鏈変互涓嬬敘(ch菐n)鈥︹€�
鍐ぉ鍒颁簡锛屽瘨娴佷篃渚�(l谩i)浜�锛岄禎姣涜埇鐨勫ぇ闆极澶╅鑸�锛屾暣鍊�(g猫)涓栫晫绌夸笂浜嗙櫧鑹茬殑澶栬。銆傚湪婕暦(zh菐ng)鐨勫啲瀛ｉ噷锛屽啺澶╅洩鍦�锛屽瘨棰�(f膿ng)鍑滃喗銆傞€欏€�(g猫)鏅�(sh铆)鍊欏洶鎿捐憲閭ｄ簺鎴愬勾鐢峰コ鏈€鍥版儜鐨勫晱(w猫n)椤屾槸锛岄€欎箞鍐风殑澶�锛屽埌搴曡兘涓嶈兘閬�(gu貌)鎬х敓娲�锛熸垜鍊�?c猫)璇欘儳鐐栭摦顑欑儰鍓愭灠顎�?ji茅)鍒舵€ф閭勬槸say no锛熻畵鎴戝€戜締(l谩i)鑱�(t墨ng)鑱�(t墨ng)鍚勬柟鐨勬剰瑕�(ji脿n)銆� 涓€銆佸弽灏�(du矛)鎬х瘈(ji茅)鍒� 鎬ф闇€姹傚氨鍍忕敓娲婚渶姹� 鍙や汉浜戯細鈥滈銆佽壊锛屾€т篃?锛佹瘷璺冩嫋鐧嚗鍫冪帛妯鳖儱渚ㄧ鎯栧泭鐜疦鏈兘锛屾槸鐢熺悊鍜屽績鐞嗙殑闇€瑕併€傜鍦�(gu贸)閱�(y墨)瀛�(xu茅)灏�(du矛)绂佹涓嶅埄浜庤韩蹇冨仴搴�锛屾棭鏈夎珫鈥︹€�
鑴瘺鏈夌殑鏅�(sh铆)鍊欐槸寰堝濂虫€ф墍闂�(gu膩n)娉ㄧ殑锛屾湁鐨勫コ鎬ч潪甯告剾(脿i)缇�锛屽皪(du矛)鎰�(脿i)缇庣殑濂虫€т締(l谩i)瑾�(shu艒)锛屽墠鑷傘€佸皬鑵跨殑姹楁瘺锛岀敋鑷宠厠姣涘凡缍�(j墨ng)鎴愪簡濂瑰€戠殑蹇冪梾锛屾瘡鍒板澶╄嚚杩戯紝寰堝浜哄氨闁�(k膩i)濮嬪埄鐢ㄥ悇绋伐鍏锋簴(zh菙n)鍌欏憡鍒モ€滄瘺鎵嬫瘺鑵斥€濄€傛畩涓嶇煡锛岀鍐墠鏄劔姣涚殑鏈€浣冲绡€(ji茅)銆傛瘺鐧�(f膩)鐨勭敓闀�(zh菐ng)鎯呮硜鑸囩ó鏃�銆佸勾榻�銆佹€у垾銆佺嚐(y铆ng)椁�(y菐ng)绛夋湁闂�(gu膩n)銆傛睏姣涢噸鑸囨睏姣涘皯锛屽氨濂芥瘮浜虹殑楂樹綆鑳栫槮锛岄兘鏄?锛孎(xi脿n)璞�銆傛湁鐨勪汉瑾�(r猫n)鐐烘睏姣涢噸灏辨槸鈥滃姣涚櫏鈥濓紝閫欐槸涓嶅皪(du矛)鐨�銆傚湪澶氭瘺闁€瑷轰腑锛屽彧鏈夋サ灏戞暩(sh霉)灏辫ê鑰呭爆浜庡姣涚櫏銆傚姣涚櫏鏄寚姹椻€︹€�
鐦﹁噳鏄暥(d膩ng)鍓嶅緢澶氬コ鎬ч伕鎿囨渶澶氱殑涓€绋柟娉�锛屽洜?y脿n)妲婂▽娓磋弽?du矛)澶栧睍绀鸿嚜宸辨渶鍓嶆部鐨勯儴浣嶏紝鍥犳姣忎竴鍊�(g猫)濂虫€ч兘灏�(du矛)鑷繁闈㈤儴鐨勫舰璞℃洿闂�(gu膩n)娉�锛屾墍浠ョ暥(d膩ng)鑷繁闈㈤儴鑲ヨ儢浠ュ悗锛屽氨鎯抽€氶亷(gu貌)鍚歌剛鐦﹁噳锛岃畵鑷繁闈㈤儴褰㈣薄鏇村畬缇�锛岄偅涔堬紝灏堝浠嬬垂鍐ぉ鍚歌剛鐦﹁噳鏈夊摢浜涘収(n猫i)瀹�锛熷皥瀹朵粙绱瑰啲澶╁惛鑴傜槮鑷夐潰闋伴儴鍦ㄩ啱(y墨)瀛�(xu茅)涓婃硾鎸�?j矛ng)?c猫)闈㈤儴锛屽叿楂旇(shu艒)渚�(l谩i)鑰冲墠鍒伴〈楠�銆侀〈寮撳埌涓嬮牅绶ｆ墍鍦嶆垚鐨勯潰閮ㄥ崁(q奴)鍩�銆傚湪閫欎竴鍗€(q奴)鍩熼亷(gu貌)澶氱殑鑴傝偑鏈┎鐦﹀皬鐨勮噳褰㈤’寰楄噧鑵€傜槮闈㈤牥闋伴儴绮剧窗(x矛)鍚歌剛琛�(sh霉)鑸囪粈骞�銆佸洓鑲㈢殑绮剧窗(x矛)鍚歌剛琛�(sh霉)鈥︹€�
涓€鑸嶏細姣忓ぉ娲楁尽澶嫟娲楁尽锛屾渻(hu矛)鎶婄毊鑶氳〃闈㈠垎娉岀殑娌硅剛鍙婃甯稿瘎鐢熷湪鐨啔琛ㄩ潰鐨勪繚璀�(h霉)鎬ц弻缇ゆ礂鎺�锛屽鏄撳偡瀹冲埌鐨啔鐨勮璩�(zh矛)灞わ紝寮曡捣鐨啔鐦欑櫌锛岀毊鑶氱殑鎶垫姉鍔涗篃鏈�(hu矛)娓涘急锛屽弽鑰屽鏄撳緱鐥�銆傚缓璀帮細1銆佽€佷汉鐨啔铏曚簬璁婅杽鍜岃悗绺媭鎱�(t脿i)锛屽缓璀�7澶╂礂涓€娆�锛�70姝蹭互涓婄殑鑰佷汉锛屽彲浠ュ欢闀�(zh菐ng)鍒�10澶╂礂涓€娆�銆� 2銆佽啔璩�(zh矛)骞茬嚗鑰�锛屽缓璀�2-3澶╂礂涓€娆�銆備簩鑸嶏細闀�(zh菐ng)鏅�(sh铆)闁撴礂婢℃礂婢℃檪(sh铆)闁撻亷(gu貌)闀�(zh菐ng)鐨啔瀹规槗鑴按锛屼汉瀹规槗鐤插嫗锛岄倓鏄撳紩璧峰績鑷熺己琛€銆佺己姘�锛岃嚧浣垮啝鐙€鍕�(d貌ng)鑴堢棛鏀ｃ€佽鏍撳舰鎴�锛岀敋鑷宠獦鐧�(f膩)鍤�(y谩n)閲嶁€︹€�
鍐ぉ鍚冧粈涔堝ソ鐩搁棞(gu膩n)鍟�(w猫n)椤�
- Q锛氬啲澶�
-
A锛氶偅涔堜綘鍒风墮鐨勬檪(sh铆)鍊欏彲浠ヤ娇鐢ㄦ韩搴︾◢寰瘮杓冮珮鐨勬按锛屼絾鏄篃涓嶈兘鐢ㄥお楂樼殑锛屽缓璀版槸30°宸﹀彸鐨勬按姣旇純鍚堥仼鍙﹀鍒风墮鐨勮┍鍐ぉ鐨勬檪(sh铆)鍊欎綘鐩￠噺鍒风墮涓嶈澶敤鍔�锛屼篃涓嶈澶揩閫燂紝涓嶁€︹€�[瑭崇窗(x矛)]
- Q锛氬啲澶╃殑鐨啔
-
A锛氫綘濂�!鏍规摎(j霉)浣犺堪瑾�(shu艒)鐨勬儏娉佹垜鑰冩叜鏄晛楹荤柟,鍑虹従(xi脿n)閫欑ó鎯呮硜鏄敱浜庤繎鍏ュ啲瀛ｄ互渚�(l谩i),姗�(j墨)楂斿厤褰瑰姏浣庝笅,姗�(j墨)楂斿姛鑳藉け瑾�(di脿o)绱婁簜,楂斿収(n猫i)鏈変竴浜涜姣掑拰琛€鐔辩殑鐧ョ媭瀛樺湪.鍦ㄩ珨鍏�(n猫i)娣ょ⿳,鑸囧鐣屽洜鈥︹€�[瑭崇窗(x矛)]
- Q锛氬啲澶╄彍璀�
-
A锛氶２椋熸柟闈㈠毚(y谩n)鏍奸伒瀹堝拰椁�(y菐ng)鎴愨€滄棭鍚冨ソ,鍗堝悆椋�,鏅氬悆灏戔€濈殑椋查缈�(x铆)鎱�,灏戝悆鐢滈,閫�(j矛n)椋熼€熷害瑕佹參,绱�(x矛)鍤兼參鍜�,閫欐ǎ瀹规槗娑堝寲,澶氬枬姘�,澶氬悆浜涙按鏋滆敩鑿�,灏戝悆钁�.璨村湪鍫�(ji膩n)鎸�![瑭崇窗(x矛)]
- Q锛氬啲澶╅(y菐ng)鑵�
-
A锛� 鍦ㄩ鐧傛柟娉曚笂澶氶噰鐢ㄦ韩鑵庡姪闄�(y谩ng)娉�,骞虫檪(sh铆)鍙椋熷嫊(d貌ng)鐗╄厧,鐙楄倝, 楣胯倝,楹婚泙,榛冮睌,娉ラ皪,铦�,鍏洖,鏍告浠�,榛戣眴绛�;閭勯爤閰嶅悎椋熺敤涓€浜涘浐绮鹃椋熷搧,濡傝姟瀵�(sh铆),钃瓙,灞辫棩,浜斿懗瀛�,閲戞鈥︹€�[瑭崇窗(x矛)]
- Q锛氬啲澶╃殑鐤戞儜..
-
A锛氬悓鎯呬綘鐨勬儏娉�锛屼笉閬�(gu貌)閫欐柟闈㈡垜涔熸矑(m茅i)鏈夌稉(j墨ng)椹�(y脿n)[瑭崇窗(x矛)]
浠婃棩鎺ㄨ枽
- 涓€绋毊鑶氱梾锛屼笉鍚岀ó鍔囩棝锛岃鎯�3椤炲嵄闅�(xi菐n)鍥犵礌
- 杓稿嵉绠￠€犲奖杓诲皠鏈�(hu矛)褰遍熆鎳峰瓡锛熻閬块枊(k膩i)閫�5澶ц鍗€(q奴)锛�
- 鑵﹀崚涓悗閬虹櫏濡備綍閫�(j矛n)琛屽悍寰�(f霉)锛熼€�6绋悍寰�(f霉)娌荤檪鏂规硶鏈�(hu矛)鏈夊公鍔�锛�
- 闈炲鍒╅叜鐢ㄤ簬寤ｆ硾蹇冭“鎮ｈ€呯殑澶氶爡(xi脿ng)鐮旂┒鍗冲皣鍟熷嫊(d貌ng)
- 銆愮緤鍩庡ソ閱�(y墨)鐢熷皥瑷(sh铆)閷勩€戜腑灞卞ぇ瀛�(xu茅)鑵槫闃叉不涓績鍏�(n猫i)绉戝嫉鍔涙暀鎺�
- 灏嬫壘閯�(xi膩ng)鏉戝ソ閱�(y墨)鐢燂細娴蜂笂绲茬盯涔嬭矾璧烽粸(di菐n)閯�(xi膩ng)閱�(y墨)鐨勮浕璁婁箣璺�
- 銆�3.24绲�(ji茅)鍚堢梾闃叉不鏃ャ€戜竴浣嶁€滆€佹湅鍙嬧€濆拰涓€鍊�(g猫)鈥滆€佸铔嬧€�
- 瑗挎櫘鏈�(hu矛)钀藉箷绱呬簯鍒惰棩鐩婅偤姝㈠挸鑶犲泭闁�(k膩i)鍟熸柊绡囩珷
灏堝绛旂枒
鐕�(y铆ng)椁�(y菐ng)椋查闋婚亾鐔遍粸(di菐n)灏堝崁(q奴)
瀛曢叜浣庡悆浠€涔堝ソ鎳峰瓡鍒濇湡涓嶈兘鍚冧粈涔�
鑳冪柤鍚冧粈涔堥鐗�
鎳峰瓡涓嶈兘鍚冧粈涔�
鎰熷啋浜嗗悆浠€涔堥鐗�
渚跨鍚冧粈涔堝ソ
鎳峰瓡鍚冧粈涔堟按鏋滃ソ
鑳冧笉鑸掓湇鍚冧粈涔堝ソ
鍟�(w猫n)閱�(y墨)閫氭渶鏂板晱(w猫n)绛�
鏂板啝闄�(y谩ng)浜嗕箣鍚庣殑鐧ョ媭鏈夊摢浜�鏂板啝绗簩娆￠櫧(y谩ng)浜嗘槸涓嶆槸鎷夎倸瀛�
鏂板啝濡備綍鍒ゆ柗瀛╁瓙鏄惁闄�(y谩ng)浜�
鏂板啝浜屾寰�(f霉)闄�(y谩ng)鐨勭櫏鐙€鏈夊摢浜�
鏂板啝闄�(y谩ng)涓夋蹇呮
鏂板啝鐝�(xi脿n)鍦ㄥ京(f霉)闄�(y谩ng)鐨勪汉鏈変粈涔堢櫏鐙€
鏂板啝绗簩娆″京(f霉)闄�(y谩ng)鏈�(hu矛)鍌虫煋浜哄棊
鏂板啝绗簩娉㈤櫧(y谩ng)鐨勭櫏鐙€鏈夊摢浜�
鏂板啝绗簩娆￠櫧(y谩ng)鎬у咕澶╄兘杞�(zhu菐n)闄�
鏂板啝鐝�(xi脿n)鍦ㄩ倓娌�(m茅i)鏈夐櫧(y谩ng)鐨勪汉澶氬棊
鏂板啝绗簩娆″京(f霉)闄�(y谩ng)浠€涔堢櫏鐙€
鏂板啝2娆￠櫧(y谩ng)浜嗕粈涔堢櫏鐙€
鏂板啝閭勬湁绗簩娆￠櫧(y谩ng)鍡�
鏂板啝闄�(y谩ng)鎬ф€庢ǎ鎵嶇煡閬撹綁(zhu菐n)闄颁簡
鏂板啝闄�(y谩ng)瀹屼箣鍚庨倓鏈�(hu矛)闄�(y谩ng)绗簩娆″棊
鏂板啝浜屾寰�(f霉)闄�(y谩ng)鏄粈涔堝師鍥�
鏂板啝闄�(y谩ng)搴峰悗浜屾鎰熸煋鐨勭櫏鐙€
鏂板啝濡備綍鍒ゆ柗鍋囬櫧(y谩ng)鍜岀湡闄�(y谩ng)
鏂板啝绗簩娆￠櫧(y谩ng)浜嗘槸浠€涔堢櫏鐙€
鏂板啝鍑虹従(xi脿n)闄�(y谩ng)鎬у氨鏄劅鏌撲簡鍡�
鏂板啝浜屾闄�(y谩ng)浜嗘€庝箞娌荤檪
鏂板啝绗簩娉㈤櫧(y谩ng)浜嗗棊
鏂板啝浜屾闄�(y谩ng)鎬т粈涔堟剰鎬�
鏂板啝濡傛灉涓€鐩翠笉闄�(y谩ng)鏈�(hu矛)鎬庝箞妯�
鏂板啝浜岄櫧(y谩ng)浜嗕粈涔堢櫏鐙€
鏂板啝娌�(m茅i)闄�(y谩ng)鐨勪汉瑾�(shu艒)鏄庝粈涔�
鏂板啝鍖椾含澶╂触浜屾闄�(y谩ng)
鏂板啝鍖椾含浜屾闄�(y谩ng)鐨勪汉
鏂板啝浜屾闄�(y谩ng)鐨勫湴鍗€(q奴)
鏂板啝鏈€杩戜簩娆￠櫧(y谩ng)鐨勪汉澶氬棊
鏂板啝浜屾寰�(f霉)闄�(y谩ng)楂樺嘲鍦ㄤ粈涔堟檪(sh铆)鍊�
鏂板啝浜旀湀浠界浜屾尝闄�(y谩ng)
鏂板啝闄�(y谩ng)浜嗕箣鍚庡氨涓€鐩村毚(y谩n)閲嶅け鐪�
鏂板啝浜屾寰�(f霉)闄�(y谩ng)鏈�(hu矛)姝诲棊
鏂板啝濡傛灉绗簩娆￠櫧(y谩ng)浜嗘€庝箞杈�
鏂板啝绗簩娉㈤櫧(y谩ng)浜嗘渶鏂�
鏂板啝涓湅(gu贸)浜烘槸鍚﹀繀闋堥櫧(y谩ng)涓€娆�
鏂板啝鐝�(xi脿n)鍦ㄩ櫧(y谩ng)绗簩娆＄殑浜哄鍡�
鏂板啝绗簩娆￠櫧(y谩ng)鐨勪汉澶氬棊
鏂板啝绗簩娆￠櫧(y谩ng)楂樺嘲鏈熸槸浠€涔堟檪(sh铆)鍊�
